GRN and Ataxia: No obvious hindlimb weakness or ataxia phenotypes were observed in 5‐month‐old and 16‐month‐old Tmem106b+/−Grn−/− and Tmem106b−/−Grn+/− mice (our unpublished observations), suggesting that total loss of both PGRN and TMEM106B is required for the development of these behavioral phenotypes.