FGFR1 and breast carcinoma: Amplification of FGFR1 is found in several types of cancer (e.g., nonsmall cell lung carcinoma, head and neck tumors, breast cancer, ovarian cancer, bladder cancer, and rhabdomyosarcoma) [10, 11, 22, 38, 52], with a frequency of up to 10% in breast cancer [61].