CXCL10 and infection: Infection of PMA‐treated THP‐1 shSAMHD1 cells with HIV‐1 GFP that had been produced in the presence of increasing doses of LPV led to a virus and LPV dose‐dependent increase in the expression of ISGs CXCL‐10, IFIT‐2 and MxA at the mRNA level (Fig 1D–F), and CXCL‐10 protein secretion (Fig 1G).