The polycyclic aminothiazole derivative N-(2-{[4-(dimethylamino)phenyl]amino}-4′-methyl-4,5′-bi-1,3-thiazol-2′-yl) propanamide is a potent DC-SIGN ligand 1 (DCSL1) [8], alleviates fibrosis, reduces pro-fibrotic macrophage polarization, and increases anti-inflammatory interleukin-10 (IL-10) levels in the bleomycin-induced lung fibrosis model in young mice [16]. Here, IL10 is linked to pulmonary fibrosis.