Hester et al. showed that EP3 expression significantly decreases with higher grades of cervical intraepithelial neoplasia (Hester et al. 2019) and the expression levels of EP3 correlate with tumour stage as well as clinical outcome as Heidegger et al. could confirm (Heidegger et al. 2017). The gene discussed is PTGER3; the disease is cervical intraepithelial neoplasia.