In comparison to other cancer types, STS showed high expression of PSMB5, PSMB6 and PSMB7, the subunits of the constitutive proteasome and low levels of PSMB8, PSMB9 and PSMB10, the subunits specific to immunoproteasomes (Fig. 1a). The gene discussed is PSMB6; the disease is telomere syndrome.