NRAS and melanoma: Several studies showed that NRAS mutations may result in an inferior clinical outcome with a shorter Melanoma-Specific Survival (MSS) (Devitt et al., 2011; Ellerhorst et al., 2011), although partially debated (Omholt et al., 2003; Akslen et al., 2005; Edlundh-Rose et al., 2006; Ugurel et al., 2007; Ellerhorst et al., 2011).