In a Chinese cohort of 412 melanoma patients, nonsynonymous MTOR mutations were found by NGS analysis in acral, mucosal, cutaneous melanomas (with and without chronic sun-induced damage), and unknown primary subtypes, with a frequency of 11.0, 14.3, 3.4–6.7, and 11.1%, respectively (Kong et al., 2016). Here, MTOR is linked to melanoma.