ACE2 and acute respiratory distress syndrome: The plausible mechanism of actions includes inhibition of angiotensin converting enzyme 2 (ACE-2) present on the cell surface for virus entry (by reduction of glycosylation in the enzyme) (4, 5), inhibition of release of viral particles into intra-cellular space (6, 7), and an anti-inflammatory effect (inhibition of interleukin-6, the tumor necrosis factor, the aberrant interferon, and other pro-inflammatory cytokines that cause lung injury leading to acute respiratory distress syndrome) (6, 8).