• Well-differentiated pancreatic neuroendocrine tumor (PanNET)      ▪ Grade 1 (low), Ki67 <3%      ▪ Grade 2 (intermediate), Ki67 3–20%      ▪ Grade 3 (high), Ki67 >20%   • Poorly differentiated pancreatic neuroendocrine carcinoma (PanNEC), high-grade, Ki67 >20%. The gene discussed is MKI67; the disease is pancreatic endocrine carcinoma.