In a study concentrating on RNA binding proteins (RBPs), the authors referred to published literature as well as oncogenic databases and conducted functional verification studies; they identified the sorbin and SH3 domain containing 2 (SORBS2) out of a pool of RBPs, as a suppressor of metastatic colonization of ovarian cancer, which exerted tumor suppressive function by dampening cancer invasiveness and repolarizing MDSCs and TAMs (Zhao L. et al., 2018). This evidence concerns the gene SORBS2 and cancer.