ANXA5 and Huntington disease: However, in HD patients, we observed a significant increase in the plasma concentration of microvesicles derived from proinflammatory monocytes (CD14+ Annexin V+CD16+MV) as compared with elderly, CKD4-5 and KT patients (4.6 ± 0.1 vs. 3.2 ± 0.1, 3.2 ± 0.1, and 3.5 ± 0.1 MV/μl, p < 0.001, respectively), (Figure 6C).