Furthermore, this study established that 3,5,4′-trihydroxy-trans-stilbene (trade name: Resveratrol), a polyphenol compound found in red-wine, grapes, berries and peanuts and believed to act as an antioxidant, also hindered HCC progression driven by HSCs through targeting Gli-1. Here, GLI1 is linked to hepatocellular carcinoma.