MiR-145 can induce posttranscriptional silencing of its targeted genes by binding to the mRNA 3’-UTR or linc-ROR specific sites, indicating that linc-ROR can act as a ceRNA to decrease miR-145 in PC cells, thereby activating expression of Nanog, thus leading to the proliferation of pancreatic cancer stem cells (PCSCs) (Gao et al., 2016). Here, LINC-ROR is linked to pachyonychia congenita.