ASAH1 and keloid: It is also possible that the familial tendency of keloids and the fact that black people develop keloids much more readily than Caucasians relate to the presence of one or more single nucleotide polymorphisms that promote VEC dysfunction: one recent candidate is a variant of the N-acylsphingosine amidohydrolase-1 (ASAH1) gene, which is expressed by VECs and mural cells (Santos-Cortez et al., 2017).