Since LAMC2 promotes the proliferation and survival of cancer cells (Garg et al., 2014; Sato et al., 2014), and keloids are characterized by excessive fibroblast proliferation and resistance to apoptosis (Funayama et al., 2003), we also asked whether LAMC2 secretion by VECs could promote keloid fibroblast proliferation and downregulate apoptosis. This evidence concerns the gene LAMC2 and keloid.