IL10 and myocardial infarction: This is true in different types of tissue, including models of pulmonary fibrosis and myocardial infarction (Nakagome et al., 2006; Rajasingh et al., 2006), in which IL-10 influences proteolytic enzymes to lyse the ECM and decrease macrophage TGF-β1 expression to prevent fibrosis (Nakagome et al., 2006; Shi et al., 2013, 2014).