The specific mechanism of action of each SNP differs, varying from inducing the differential expression of several genes of the LCE family, associated with breast cancer in African American women (section 2.2), to inducing the malfunctioning of several transcription factors implicated in cancer, e.g., CTCF, EP300, YY1, LMO2 (section 3.2). This evidence concerns the gene EP300 and cancer.