IGHE and allergic disease: In a prospective cohort study of 119 children with IgE-mediated CMA, a multivariate analysis of risk factors for the occurrence of AM revealed that the use of an extensively hydrolyzed casein-based formula (EHCF) represented a protective factor for other allergic diseases, compared to other hypoallergenic formulas or soy-based formulas (OR 0.76; 95% CI: 0.149–0.945, p = 0.038) (71).