Additionally, it is speculated that increased DC-SIGN expression in senescent monocytes may also facilitate other microbial infections, including infections with viruses such as influenza virus, human immunodeficiency virus, Ebola virus, hepatitis C virus, cytomegalovirus, and SARS coronavirus; infections with bacteria such as Mycobacterium tuberculosis and Helicobacter pylori; and infections with parasites such as Leishmania pifanoi, and that these pathogens need DC-SIGN as an infectious receptor (Khoo et al., 2008). The gene discussed is CD209; the disease is infection.