Among the genes with prognostic significance in our module of immune-related ceRNA network, there were AML related reports about CBX2, CCND2, ERG, IGF1R, LARP1, LFNG, NUDT16, POU2F2, PTAFR, RAB3D, SIGLEC7, SRSF6, TNFAIP2, TRIB1, ZBTB5, and ZNRF1, the most reported of which were ERG, CCND2, and IFG1R. ERG translocation was involved in the occurrence and development of AML, and high expression of ERG was a poor prognostic factor for patients with normal karyotype AML (33, 34). The gene discussed is ZNRF1; the disease is acute myeloid leukemia.