Recently, it has been shown that MSCs isolated from mammary AT of patients with BC, express high levels of brain-derived neurotrophic factor (BDNF), neurogenic locus notch homolog protein 1 (NOTCH1) and cytoskeletal Vimentin, and reduction of growth differentiation factor 15 (GDF15), IGF1, MMP2, platelet-derived growth factor receptor b (PDGFRB) and TGFβ. This evidence concerns the gene NOTCH1 and breast cancer.