BABAM2 and esophageal squamous cell carcinoma: The CCK-8 assay revealed that the viability of two ESCC cell lines, KYSE450 and KYESE140, was significantly decreased when BRE was knocked down (Figure 2A), whereas BRE overexpression significantly increased the viability of the Eca109 and TE-1 ESCC cell lines (Figure 2B).