However, previous studies showed that when ABL1 expression was inhibited by nilotinib, the number of cells in the G0/G1 phase was increased while the number of cells in S and G2/M phases was decreased (30), which is contradictory to the finding in this study that downregulation of ABL1 arrested CRC cells at S phase. This evidence concerns the gene ABL1 and colorectal carcinoma.