Chondroitin sulfate PG 4, commonly referred to as neuron-glial antigen 2 (NG2), contributes to the stabilization of interaction between cell and substratum on endothelial basement membranes, especially at the early spreading stage of melanoma cells (26) In addition, CS PG 4 is a suggested biomarker in glioblastoma (GBM) (27). Here, CS is linked to glioblastoma.