AKT1 and neoplasm: Furthermore, azurin is able to inhibit tumor angiogenesis by non-competitively inhibiting the phosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), as well as the phosphorylation of downstream VEGFR2 targets FAK (focal adhesion kinase), AKT proteins (protein kinase B), and basic fibroblast growth factor (bFGF) (22).