CD274 and extranodal nasal NK/T cell lymphoma: Given the lack of response of this GI T-LPD case to a variety of therapeutics, high expression of PD-L1 could be responsible for this patient's poor prognosis as EBV-encoded LMP1 upregulated PD-L1, and elevated PD-L1 resulted in adverse clinical course in NKTCL cases (10).