TP53 and hepatocellular carcinoma: The commonly targeted pathways by dysregulated miRNAs in HBV-HCC include the Janus kinase/signal transducer (JAK/STAT), phosphoinositide 3-kinase/mitogen-activated protein kinase (PI3K)/AKT and MAPK, Wingless-related integration site/beta-catenin (WNT/β-Catenin) and TP-53 pathways (40, 64–73).