miRNA-122 targets multiple genes, including BCL9, Bcl-w, NDRG3, cyclin G1, ADAM17, ADAM10, G6PD, and pituitary tumor-transforming gene 1 (PTTG1) binding factor (PBF), all of which have been implicated in tumor development (53–60). This evidence concerns the gene PTTG1 and neoplasm.