As expected, our data demonstrated that TNRs and SUVSD were significantly lower in the IDH-mutant group compared with those IDH-wildtypes, which are consistent with those of Kim et al. (15) 11C-MET PET derived SUVSD showed the most excellent ability to identify whether glioma had an IDH mutation or not besides other MET PET metrics. The gene discussed is IDH1; the disease is glioma.