The other signaling pathways, including the cell cycle, PI3K, P53, Notch, Myc, Hippo, Nrf2, and TGFβ pathways, were not significantly altered between the two HCC immunogram clusters (two-sided Fisher's exact test, P > 0.05; Figure 5 and Table 2). The gene discussed is MYC; the disease is hepatocellular carcinoma.