CD36 and colorectal carcinoma: To test whether blocking fatty-acid uptake via CD36 has an effect on CRC cell proliferation, primary CRC cells, Pt 93 and Pt 130, were treated with the chemical CD36 inhibitor sulfosuccinimidyl oleate (SSO), which binds to CD36 via Lys164 in the hydrophobic cavity thereby impairing CD36-mediated fatty acid uptake (18, 34), at 100 μM in both normal and serum free medium (SFM) conditions.