Figure 5 shows the main biological effects of the key targets of CKI, in addition to the major enriched pathways mentioned above; the whole biological process also involves ErbB signaling pathway, MAPK signaling pathway, and NF-kappa B signaling pathway.  Figure 6 illustrates the interaction among compounds, targets, and pathways of CKI in treating BC. The gene discussed is EGFR; the disease is breast cancer.