Although rarely reported with MPM, there is accumulating evidence showing CKS2 is upregulated in many types of tumor as a prognostic factor, including hepatocellular carcinoma, colorectal cancer, bladder cancer, breast cancer, gastric cancer and epithelium ovarian cancer (Kawakami et al., 2006; Shen et al., 2010; Tanaka et al., 2011; Yu et al., 2015; Huang et al., 2019; Xu et al., 2019). Here, CKS2 is linked to colorectal cancer.