For the yellow module, we built a genome network which was mapped by three cell proliferation pathways (KEGG): “cell cycle,” “DNA replication,” and “oocyte meiosis.” EZH2 (the transcription factor with significant protein-altering mutations) was selected in the molecular regulation network most probably regulating the oncogenesis of HCC (Figure 7B). The gene discussed is EZH2; the disease is hepatocellular carcinoma.