For example, the lncRNA MALAT1 is overexpressed with high risk HPVs infection (Jiang et al., 2014; Yang et al., 2015) while the lncRNA MALAT1/miR-145-5p/AKAP12 axis has been verified in prostate cancer (Xue et al., 2018). This evidence concerns the gene AKAP12 and Familial prostate cancer.