KEGG pathway enrichment analysis demonstrated that up-regulated genes were significantly enriched in protein digestion and absorption, ECM-receptor interaction and PI3K/Akt signaling pathway while down-regulated genes were enriched in mineral absorption and metabolic pathways, and all those are significant pathways in various cancer types been reported previously (Boroughs and DeBerardinis, 2015; Dimitrova and Arcaro, 2015; Wang S.S. et al., 2017; Slattery et al., 2018). Here, AKT1 is linked to cancer.