Kikuchi et al. (2018) performed microarray analyses using PAH-PASMCs and found that, compared with the genes in control PASMCs, 1,858 genes had significantly changed (P < 0.05), of which selenoprotein P (SeP) was up-regulated 32 times compared with its expression in control PASMCs. Here, SELENOP is linked to pulmonary arterial hypertension.