To further analyze the effect of GPRC6a on GVHD, we performed alloSCTs in the BALB/c→B6 murine GVHD model using mice deficient for GPRC6a (GPRC6a–/–, B6 background) either as recipients or donors of alloSCT. The gene discussed is GPRC6A; the disease is graft versus host disease.