FPR1 and cystic fibrosis: Interestingly, although CF animals exhibited a slight increase in the global number of neutrophils (Figures 1D,E), fMLP-stimulated neutrophil chemotaxis revealed that CF neutrophil responses are indistinguishable from their control counterparts (14) (Figure 1F), suggesting that elevation in neutrophil numbers at wound is neither due to an overall increase in neutrophils within CF fish nor to a generalized upregulation of chemotaxis in CF neutrophils.