However, in another study, the ILC2s (as measured by the production of IL-5 and IL-13) pre-activation via intra-tracheal IL-33 administration before the lethal S. aureus sepsis protects the host from ALI and death via pulmonary eosinophilia induction, which clears the pathogen from the lungs and suppresses neutrophilia (221). The gene discussed is IL33; the disease is acute respiratory distress syndrome.