Also, the NLR Family Pyrin Domain Containing 3 (NLRP3) activation in BECs during various pneumonia-causing bacterial (K. pneumoniae, S. pneumoniae, S. aureus, C. pneumoniae, and L. pneumophila) infections protects the host from infections (Figures 2A,B) (63, 76, 77). The gene discussed is NLRP3; the disease is pneumonia.