Also, the NLR Family Pyrin Domain Containing 3 (NLRP3) activation in BECs during various pneumonia-causing bacterial (K. pneumoniae, S. pneumoniae, S. aureus, C. pneumoniae, and L. pneumophila) infections protects the host from infections (Figures 2A,B) (63, 76, 77). Here, NLRP3 is linked to susceptibility to pneumonia measurement.