XCL1 and crescentic glomerulonephritis: In fact, the pathological role of XCL1-XCR1 axis has been implicated in numerous chronic inflammatory diseases, including rheumatoid arthritis, inflammatory arthritis, Crohn's disease, acute allograft rejection, autoimmune disorders, encephalomyelitis, crescentic glomerulonephritis, and inflammatory bowel disease (18–23).