IFNG and infection: Specifically, our analyses found a decrease in CD49a+ CD107a+ TNFα+ IFNγ− NK cells, with a simultaneous increase in CD49a+ CD107a+ TNFα− IFNγ+ NK cells and the non-responsive CD49a+ CD107a− TNFα− IFNγ− NK cell population following infection, suggesting both pathogenic and inflammatory changes in the NK cell functional profile.