More recently, a cluster of DCs named mregDCs (mature DCs enriched in immunomodulatory molecules) co-expressing immunoregulatory genes (Cd274, Pdcd1lg2, and Cd200) and maturation genes (Cd40, Ccr7, and Il12b) was found in single cell analysis of mouse and human non-small cell lung cancer (NSCLC) DC infiltrate (44). The gene discussed is IL12B; the disease is non-small cell lung carcinoma.