AST/ALT serum levels in organ donors more than three times increased above normal limits was a significant risk factor for PDF and PNF/Re-LT (RR 4.15, 95%CI 1.39–12.41; p = 0.024) as well as for early NAS (RR 5.54, 95%CI 1.62–18.99; p = 0.003). The gene discussed is GPT; the disease is neonatal abstinence syndrome.