IL17A and infection: •  The parasite loads in the liver and spleen were lower at weeks 4 and 6 post-infection. •  Mice produce higher IL-17A levels in both spleen and liver. •  Restimulation splenocyte with L. infantum lysate leads to more IL-17A production. •  Higher CXCL1expression was observed in the spleen, which causes a peak in neutrophil migration at week 4 post-infection in the spleen and liver. •  When IL-17 was blocked, the mice become as susceptible as the C57BL/6 control.