EBI3 and infection: EBI3−/− C57BL/6 mice also display greater susceptibility to L. major infection compared to C57BL/6 wild-type mice, with the maximum differences in the parasites loads and lesion sizes at the sixth-week post-infection; the lesions and parasite load are reduced from the eighth week, and lesions are entirely resolved till 14th week in EBI3−/− mice (69).