Age-related low-grade chronic inflammation, called inflamm-aging, is known for its elevated inflammatory cytokines, such as interleukin (IL)-6, IL-1β, and tumor necrosis factor (TNF)-α in serum (2–4), and it is considered a risk factor that triggers age-related diseases such as heart diseases or cerebral infarction (5). The gene discussed is TNF; the disease is cerebral infarction.