Using a scRNAseq approach, another DC cluster (Cd209a+Cd74+Flt3+H2-Eb1+DC cluster) containing both Cd209a+monocyte-derived DCs and putative mature/classical DCs, together with two macrophage populations (inflammatory macrophages enriched in IL1b and TREM2high macrophages), were detectable in mouse atherosclerotic aorta, where DCs as a major atherosclerosis-associated cell population represented 14.9% of total CD45+ cells and showed strong expression of IL1b (149). The gene discussed is IL1B; the disease is atherosclerosis.