Furthermore, the sequencing of circRNAs within KSHV-infected primary effusion lymphoma (PEL) cells showed that KSHV circRNAs (including circvIRF4 and circPAN/K7.3) were expressed in these cells, and were found to originate from the vIRF4 locus and the PAN region, respectively (Toptan et al., 2018). This evidence concerns the gene KRT73 and primary effusion lymphoma.