MBL2 and chronic hepatitis B virus infection: Other factors, such as alcohol, aflatoxin, gut microbiota, mannose-binding lectin (MBL) genotype, and also miRNAs, can affect the progression of chronic hepatitis B (Ohnishi et al., 1982; Handin et al., 2003; Chong et al., 2005; Sagnelli et al., 2018; Sadri Nahand et al., 2019).