MKI67 and panhypopituitarism: The presence of a macroprolactinoma was correlated with male gender (r = 0.443, P = 0.026), high PRL level at diagnosis (r = 0.710, P < 0.001), and the presence of panhypopituitarism (r = 0.623, P = 0.001), but not with age at diagnosis, BMI SDS, height SDS, and the Ki-67 index (Table 2).