TERT and thyroid gland papillary carcinoma: In support of the TCGA data, in a large study of thyroid cancers in which anaplastic carcinoma coexisted with papillary carcinoma, a multivariate comparison between the antecedent papillary carcinoma components and control papillary carcinomas without anaplastic transformation showed that TERT mutations were independently associated with anaplastic transformation (23).