There was found a weak decrease of luteinizing hormone (LH) (SMD: −0.36, 95% CI: −3.24 to 2.52; I2 = 100%, n = 5) and anti-Müllerian hormone (AMH) (SMD: −0.92, 95% CI: −2.06 to 0.22; I2 = 95%, n = 2), and a weak increase of estradiol (SMD: 1.04, 95% CI: −2.05 to 4.12; I2 = 100%, n = 4) in MetS cases. This evidence concerns the gene PLOD1 and metabolic syndrome.