However, no studies on neurofilament light chain (NFL) as a cerebrospinal fluid (CSF) marker of axonal neurodegeneration or on YKL-40 as a CSF marker of glial neuroinflammation have been conducted in IBMPFD patients with <i>VCP</i> mutations. Here, NEFL is linked to inclusion body myopathy with Paget disease of bone and frontotemporal dementia.